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1

Analyte-driven disassembly and turn-on fluorescent sensing in competitive biological media

Beatty, Meagan A., Borges-González, Jorge, Sinclair, Nicholas J., Pye, Aidan T., Hof, Fraser

Journal:

Journal of the American Chemical Society

Year:

2018

Language:

english

File:

PDF, 743 KB

english, 2018

2

Molecular Encapsulation

Fraser Hof, Stephen L. Craig, Colin Nuckolls, Julius Rebek, Jr.

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 902 KB

english, 2002

3

Insights into the Post-Translational Methylation of Arginine from Studies of Guanidinium–Water Nanodroplets

Keri McQuinn, J. Scott McIndoe, Fraser Hof

Journal:

Chemistry - A European Journal

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

4

Synthetic trimethyllysine receptors that bind histone 3, trimethyllysine 27 (H3K27me3) and disrupt its interaction with the epigenetic reader protein CBX7

Tabet, Sara, Douglas, Sarah F., Daze, Kevin D., Garnett, Graham A.E., Allen, Kevin J.H., Abrioux, Emma M.M., Quon, Taylor T.H., Wulff, Jeremy E., Hof, Fraser

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 917 KB

english, 2013

5

Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7)

Simhadri, Chakravarthi, Daze, Kevin D., Douglas, Sarah F., Quon, Taylor T. H., Dev, Amarjot, Gignac, Michael C., Peng, Fangni, Heller, Markus, Boulanger, Martin J., Wulff, Jeremy E., Hof, Fraser

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.40 MB

english, 2014

6

A Terphenyl Scaffold for π-Stacked Guanidinium Recognition Elements

Wang, Xing, Sarycheva, Olga V., Koivisto, Bryan D., McKie, Aaron H., Hof, Fraser

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 126 KB

english, 2008

7

In Vitro Assessment of Putative PD-1/PD-L1 Inhibitors: Suggestions of an Alternative Mode of Action

Blevins, Derek J., Hanley, Ronan, Bolduc, Trevor, Powell, David A., Gignac, Michael, Walker, Kayleigh, Carr, Mark D., Hof, Fraser, Wulff, Jeremy E.

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 2.34 MB

english, 2019

8

Titelbild: Angew. Chem. 9/2002

Fraser Hof, Stephen L. Craig, Colin Nuckolls, Julius Rebek, Jr.

Journal:

Angewandte Chemie

Year:

2002

File:

PDF, 64 KB

2002

9

Molekulare Verkapselung

Fraser Hof, Stephen L. Craig, Colin Nuckolls, Julius Rebek, Jr.

Journal:

Angewandte Chemie

Year:

2002

Language:

german

File:

PDF, 912 KB

german, 2002

10

Solid-State and Solution Studies of a Tetrameric Capsule and Its Guests

Darren W. Johnson, Fraser Hof, Peter M. Iovine, Colin Nuckolls, Julius Rebek, Jr.

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

11

Cover Picture: Angew. Chem. Int. Ed. 9/2002

Fraser Hof, Stephen L. Craig, Colin Nuckolls, Julius Rebek, Jr.

Journal:

Angewandte Chemie International Edition

Year:

2002

File:

PDF, 64 KB

2002

12

Solid-State and Solution Studies of a Tetrameric Capsule and Its Guests

Darren W. Johnson, Fraser Hof, Peter M. Iovine, Colin Nuckolls, Julius Rebek, Jr.

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

13

Acetylcholine Recognition by a Deep, Biomimetic Pocket

Fraser Hof, Laurent Trembleau, Elke Christine Ullrich, Julius Rebek, Jr.

Journal:

Angewandte Chemie

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

14

A Weak Attractive Interaction between Organic Fluorine and an Amide Group

Fraser Hof, Denise M. Scofield, W. Bernd Schweizer, François Diederich

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 239 KB

english, 2004

15

Aushungern des Malaria-Erregers: Hemmer der Aspartylproteasen Plasmepsin I, II und IV

Fraser Hof, Andri Schütz, Christoph Fäh, Solange Meyer, Daniel Bur, Jun Liu, Daniel E. Goldberg, François Diederich

Journal:

Angewandte Chemie

Year:

2006

Language:

german

File:

PDF, 231 KB

german, 2006

16

Acetylcholine Recognition by a Deep, Biomimetic Pocket

Fraser Hof, Laurent Trembleau, Elke Christine Ullrich, Julius Rebek, Jr.

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

17

A Weak Attractive Interaction between Organic Fluorine and an Amide Group

Fraser Hof, Denise M. Scofield, W. Bernd Schweizer, François Diederich

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 239 KB

english, 2004

18

Starving the Malaria Parasite: Inhibitors Active against the Aspartic Proteases Plasmepsins I, II, and IV

Fraser Hof, Andri Schütz, Christoph Fäh, Solange Meyer, Daniel Bur, Jun Liu, Daniel E. Goldberg, François Diederich

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

19

A Simple Calixarene Recognizes Post-translationally Methylated Lysine

Cory S. Beshara, Catherine E. Jones, Kevin D. Daze, Brandin J. Lilgert, Fraser Hof

Journal:

Year:

2010

Language:

english

File:

PDF, 246 KB

english, 2010

20

ChemInform Abstract: Studies on the Preparation of 3,4-Disubstituted 2-Methoxypyridines.

Marcelo M. M. Pelisson, Gil Valdo Jose da Silva, Derrick L. J. Clive, Don M. Coltart, Fraser A. Hof

Journal:

Year:

1999

File:

PDF, 32 KB

1999

21

ChemInform Abstract: Highly Selective Synthesis of Heterosubstituted Aromatic Sulfamides.

Fraser Hof, Peter M. Iovine, Darren W. Johnson, Julius Rebek Jr.

Journal:

Year:

2002

File:

PDF, 30 KB

2002

22

ChemInform Abstract: Molecular Encapsulation.

Fraser Hof, Stephen L. Craig, Colin Nuckolls, Julius Rebek Jr.

Journal:

Year:

2002

File:

PDF, 24 KB

2002

23

Molecules Within Molecules: Recognition Through Self-assembly.

Fraser Hof, Jr. Rebek, Julius

Journal:

Year:

2002

File:

PDF, 24 KB

2002

24

Synthesis of exo-3-Amino-7-azabicyclo[2.2.1]heptanes as a Class of Malarial Aspartic Protease Inhibitors: Exploration of Two Binding Pockets

Martina Zürcher, Fraser Hof, Luzi Barandun, Andri Schütz, W. Bernd Schweizer, Solange Meyer, Daniel Bur, François Diederich

Journal:

European Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 813 KB

english, 2009

25

Preparation of Tröger Base Derivatives by Cross-Coupling Methodologies

Fraser Hof, Michael Schär, Denise M. Scofield, Felix Fischer, François Diederich, Sergey Sergeyev

Journal:

Helvetica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

26

Studies on the preparation of 3,4-disubstituted 2-methoxypyridines

Marcelo M. M. Pelisson, Gil Valdo José Da Silva, Derrick L. J. Clive, Don M. Coltart, Fraser A. Hof

Journal:

Journal of Heterocyclic Chemistry

Year:

1999

File:

PDF, 504 KB

1999

27

Collision-induced dissociation of protonated nanodroplets

Keri McQuinn, Fraser Hof, J. Scott McIndoe

Journal:

International Journal of Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 467 KB

english, 2009

28

Structural and functional characterization of a triple mutant form of S100A7 defective for Jab1 binding

Nathan R. West, Benjamin Farnell, Jill I. Murray, Fraser Hof, Peter H. Watson, Martin J. Boulanger

Journal:

Protein Science

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

29

A tryptophan-analog host whose interactions with ammonium ions in water are dominated by the hydrophobic effect

Amanda L. Whiting, Nicole M. Neufeld, Fraser Hof

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

30

Protein Geranylgeranylation Is Required for Osteoclast Formation, Function, and Survival: Inhibition by Bisphosphonates and GGTI-298

Dr. Fraser P. Coxon, Miep H. Helfrich, Robert Van't Hof, Saïd Sebti, Stuart H. Ralston, Andrew Hamilton, Michael J. Rogers

Journal:

Journal of Bone and Mineral Research

Year:

2000

Language:

english

File:

PDF, 3.60 MB

english, 2000

31

The Cation−π Interaction at Protein–Protein Interaction Interfaces: Developing and Learning from Synthetic Mimics of Proteins That Bind Methylated Lysines

Daze, Kevin D., Hof, Fraser

Journal:

Accounts of Chemical Research

Year:

2013

Language:

english

File:

PDF, 412 KB

english, 2013

32

Modular incorporation of 1-benzyltryptophan into dipeptide hosts that bind acetylcholine in pure water

Beshara, Cory S., Hof, Fraser

Journal:

Canadian Journal of Chemistry

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

33

Recognition Properties of Carboxylic Acid Bioisosteres: Anion Binding by Tetrazoles, Aryl Sulfonamides, and Acyl Sulfonamides on a Calix[4]arene Scaffold

Pinter, Thomas, Jana, Subrata, Courtemanche, Rebecca J. M., Hof, Fraser

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 3.12 MB

english, 2011

34

Just add tetrazole: 5-(2-Pyrrolo)tetrazoles are simple, highly potent anion recognition elements

Courtemanche, Rebecca J. M., Pinter, Thomas, Hof, Fraser

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

35

Binding trimethyllysine and other cationic guests in water with a series of indole-derived hosts: large differences in affinity from subtle changes in structure

Whiting, Amanda L., Hof, Fraser

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 779 KB

english, 2012

36

Identification and Characterization of Binding Sites on S100A7, a Participant in Cancer and Inflammation Pathways

León, Rafael, Murray, Jill I., Cragg, Gina, Farnell, Benjamin, West, Nathan R., Pace, Tamara C. S., Watson, Peter H., Bohne, Cornelia, Boulanger, Martin J., Hof, Fraser

Journal:

Year:

2009

Language:

english

File:

PDF, 2.29 MB

english, 2009

37

PROFILE: Early Excellence in Physical Organic Chemistry (Fraser Hof)

Journal:

Journal of Physical Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 129 KB

english, 2012

38

Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding

Murray, Jill I, Tonkin, Michelle L, Whiting, Amanda L, Peng, Fangni, Farnell, Benjamin, Cullen, Jay T, Hof, Fraser, Boulanger, Martin J

Journal:

BMC Structural Biology

Year:

2012

Language:

english

File:

PDF, 508 KB

english, 2012

39

Antibody-Free Reading of the Histone Code Using a Simple Chemical Sensor Array

Minaker, Samuel A., Daze, Kevin D., Ma, Manuel C. F., Hof, Fraser

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 2.12 MB

english, 2012

40

Synthesis and Self-Assembly of the "Tennis Ball" Dimer and Subsequent Encapsulation of Methane. An Advanced Organic Chemistry Laboratory Experiment

Hof, Fraser, Palmer, Liam C., Rebek, Julius

Journal:

Journal of Chemical Education

Year:

2001

Language:

english

File:

PDF, 193 KB

english, 2001

41

Dissecting the Complex Recognition Interfaces of Potent Tetrazole- and Pyrrole-Based Anion Binders

Pinter, Thomas, Simhadri, Chakravarthi, Hof, Fraser

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

42

Synthesis of Versatile Nonsymmetric Amine- and Boron-Functionalized Tröger's Base Derivatives, Including a Tröger's Base Amino Acid

Whiting, Amanda L., Dubicki, Krystyn I., Hof, Fraser

Journal:

European Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 521 KB

english, 2013

43

Medicinal chemistry in academia: molecular recognition with biological receptors

Hof, Fraser, Diederich, Fran?ois

Journal:

Chemical Communications

Year:

2004

Language:

english

File:

PDF, 1.18 MB

english, 2004

44

Chiral Microenvironments in Self-Assembled Capsules

Nuckolls, Colin, Hof, Fraser, Martín, Tomás, Rebek, Julius

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 356 KB

english, 1999

45

New supramolecular organization for a glycoluril: chiral hydrogen-bonded ribbons

Johnson, Darren W., Palmer, Liam C., Hof, Fraser, Iovine, Peter M., Rebek, Julius

Journal:

Chemical Communications

Year:

2002

Language:

english

File:

PDF, 376 KB

english, 2002

46

Determining the effects of salt, buffer, and temperature on the complexation of methylated ammonium ions and methyllysines by sulfonated calixarenes

Daze, Kevin D., Jones, Catherine E., Lilgert, Brandin J., Beshara, Cory S., Hof, Fraser

Journal:

Canadian Journal of Chemistry

Year:

2013

File:

PDF, 821 KB

2013

47

Kinetically Stable Complexes in Water: The Role of Hydration and Hydrophobicity

Biros, Shannon M., Ullrich, Elke C., Hof, Fraser, Trembleau, Laurent, Rebek, Julius

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 324 KB

english, 2004

48

Emergent Conformational Preferences of a Self-Assembling Small Molecule: Structure and Dynamics in a Tetrameric Capsule

Hof, Fraser, Nuckolls, Colin, Craig, Stephen L., Martín, Tomás, Rebek, Julius

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 201 KB

english, 2000

49

Supramolecular hosts that recognize methyllysines and disrupt the interaction between a modified histone tail and its epigenetic reader protein

Daze, Kevin D., Pinter, Thomas, Beshara, Cory S., Ibraheem, Andreas, Minaker, Samuel A., Ma, Manuel C. F., Courtemanche, Rebecca J. M., Campbell, Robert E., Hof, Fraser

Journal:

Chemical Science

Year:

2012

Language:

english

File:

PDF, 423 KB

english, 2012

50

Minimalist Synthetic Host with Stacked Guanidinium Ions Mimics the Weakened Hydration Shells of Protein–protein Interaction Interfaces

Wang, Xing, Post, Joshua, Hore, Dennis K., Hof, Fraser

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 2.64 MB

english, 2014